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of Biophysics and Soft Matter

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Grafik: SignalProcessingInTheRetina_jpg

Signal processing in the retina
Immunohistochemistry with fluorescently labeled antibodies as molecular tools allows visualization of neurons. Several bipolar cell types are shown in a vertical view of the inner part of a mouse retina. Vision starts when the absorption of light quanta elicits an electrical response in photoreceptors. However, before the signal is relayed from the eye to the brain, it is analyzed within the retina. Already at the very first synapse of the visual system, parallel processing is initiated when photoreceptors relay their information to about 12 different types of bipolar cells. A systematic analysis revealed that each bipolar cell type expresses a unique set of ion channels which in concert shape the cellular response.

Cellular Biophysics:
Frank Müller

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