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SenSitus

Fast rotational matching methods for the structure determination of mega-dalton subcellular machines

Since 2004, Forschungszentrum Jülich participates in the project "Fast rotational matching methods for the structure determination of mega-dalton subcellular machines". This work is part of an international collaboration with partners in Japan, France and the USA. It is supported by a grant from the Human Frontier Science Program (Grant RGP0026/2003). Within this project our group is working on SenSitus, a program for the interactive fitting of high-resolution structures (e.g. proteins) into low-resolution density distributions of macromolecular complexes. This program also employs virtual reality techniques (namely "haptic rendering" and stereoscopic view).

Partners

  • Central Institute for Applied Mathematics, Forschungszentrum Jülich
  • University of Texas Health Science Center at Houston
  • Laboratoire de Genetique des Virus (CNRS, France)
  • Department of Biosciences (Teikyo University, Japan)

The project was funded by the Human Frontier Science Program (Grant RGP0026/2003).

The grant period was January 2004 until November 2007.

Publications and conference contributions

  • Oliver Passon, Stefan Birmanns, Maik Boltes, Herwig Zilken and Willy Wriggers,
    "Laplace-filter enhanced haptic rendering of macromolecules"
    Vision Modeling and Visualization 2005, G. Greiner, J. Hornegger, H. Niemann and M. Stamminger (Eds.), Akademische Verlagsgesellschaft Berlin (Proceedings of the 10th International Fall Workshop VMV, Erlangen, 16.-18. November 2005).
  • Oliver Passon,
    "Laplace-filter enhanced docking of macro molecules using VR techniques"
    Talk presented on the 2. Workshop on Virtual and Augmented Reality (September 26-27).
  • Stefan Birmanns, Oliver Passon, Maik Boltes, Chance Coble and Willy Wriggers,
    "Interactive Multi-Resolution Modeling by Adaptive Visuo-Haptic Rendering and Laplacian Filtering",
    Poster presentation at the Biophysical Society Meeting (February 12-16) in Long Beach, CA, USA.
  • Stefan Birmanns, Maik Boltes, Herwig Zilken and Willy Wriggers,
    "Adaptive Visuo-Haptic Rendering for Hybrid Modeling of Macromolecular Assemblie",
    Proceedings of the international IEEE conference on Mechatronics and Robotics 2004, 4:1351-1356, Eysoldt Verlag, Germany, ISBN: 3-938153-30-X