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Careers @ ER-C-3


We encourage excellent PhDs that consider pursuing an academic career to join our group. In particular, candidates with an aptitude in structural biology methods such as cryo-EM and X-ray crystallography combined with biochemistry expertise are encouraged to apply.
In case you are interested please contact for further details.

PhD students

There are two PhD positions available (see above) at the ER-C-3

  1. Cryo-EM of autophagy assemblies
    The successful candidate should have a master degree in biochemistry/cell biology, biophysics or related field. The candidate will be working on high-resolution cryo-EM structure determination of purified autophagy complexes and/or in situ imaging of cellular samples using correlative light and electron microscopy approaches. The goal of the ERC-3 institute is to shed light on the structural principles of the essential cellular maintenance mechanism of autophagy.

  2. Cryo-EM method development
    The successful candidate should have a master degree in bioinformatics, biophysics or related field. The candidate will be using and developing cryo-EM image processing methods to determine the 3D structures of biological macromolecules. We expect to use novel imaging approaches and apply computational methods of pattern recognition, artificial intelligence and deep learning to improve 3D reconstruction and density map interpretation methods. Familiarity with the Unix operating system is required and prior knowledge in programming will be a plus.

The candidates will be working in a creative and international environment embedded in an interdisciplinary team with colleagues ranging from electron microscopists, computer scientists, biochemists as well as cellular biologists. The 3-year PhD position is immediately available. Payment of the PhD fellow will be based on salary grade EG 13 (50%) Collective Agreement for the Civil Service (TVöD).

Forschungszentrum Jülich aims to employ more women in this area and therefore particularly welcomes applications from women. We also welcome applications from disabled persons.


Complete applications should include a CV and the name and emails of two references, along with a motivation letter, and have to be submitted to Dr. Carsten Sachse ( More detailed information on the scientific interests of the Sachse group can be found on
The received documents will be screened by an evaluating committee and, based on the expertise and the records of the scientific career; the shortlisted candidates will be invited for an interview, by teleconference if necessary.

Master students

We will also consider applications from master students with education in the areas of molecular biology, biophysics and bioinformatics. We prefer to give longer-term internships from 6 months to 1 year. Please include your motivation and contact for further details.

Additional Information

Head of ER-C-3

Structural Biology (ER-C-3)


Prof. Dr. Carsten Sachse

Phone: +49 2461 61-2030
Fax: +49 2461 61-1448

Team assistant:
Melanie Hagen

Phone: +49 2461 61-2031
Fax: +49 2461 61-1448