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Advertising division: IBG-1 - Biotechnology
Reference number: 2019M-069, Biotechnology, process engineering, computational science and engineering

Master thesis: Computational performance analysis of pleated filter cartridges

Start of work: immediately / by agreement


At the Institute for Bio- and Geoscience (IBG-1) at Forschungszentrum Jülich, computational approaches in conjunction with wet lab experiments are applied to study and optimize cell metabolism, biotechnological processes and devices. In a current collaboration with Sartorius Stedim Biotech, mathematical models of pleated filter cartridges are applied to understand and quantitatively predict the impact of pleat geometry, membrane porosity and permeability on important performance indicators of the filter device, such as water flow rate. Computational fluid dynamics (CFD) are used to predict the performance of these devices based on their internal geometry as well as material properties of the utilized membrane and nonwoven layers. The simulation results provide novel insights to the governing mechanisms at varying operating conditions, for instance operating pressure, and allow to optimize design and operation of pleated filter cartridges.

Your tasks:
The aim of this master thesis project is to develop predictive CFD models for pleated filter cartridges with given internal geometry, material properties and operating conditions. The computational geometry is to be reconstructed from high resolution CT-scansimages taken at several different operating conditions. The required material properties, such as porosity and permeability of membrane and nonwoven layers, are available from direct measurements. A mesh independence study must be performed before the simulation results are validated against independent measurements. Parametric studies with the CFD model will then be used for quantifying the impact of various design factors on the desired performance of the studied cartridges.

Your profile:

  • Very good grades in the fields of computational science and engineering or related subjects
  • Interest in biotechnology and process engineering
  • Ability to work independently and analytically in a project team
  • Experience in CFD modeling, ideally with COMSOL Multiphysics

Our offer:

  • A highly motivated working group in one of the largest research institutions in Europe
  • Excellent scientific and technical infrastructure, including CFD software and compute resources
  • Intensive support of the work at Forschungszentrum Jülich and by Sartorius Stedim Biotech
  • The master thesis is remunerated

Dr. Eric von Lieres
Forschungszentrum Jülich GmbH
Institute for Bio- and Geosciences (IBG)
IBG-1: Biotechnology

Tel.02461 61-2168